2011 Fiscal Year Final Research Report
Development and application of multi-functional hybrid-type organocatalysts based on hypervalent iodine oxidation
| Project/Area Number |
21590005
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | University of Toyama |
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Principal Investigator |
YAKURA Takayuki 富山大学, 大学院・医学薬学研究部(薬学), 教授 (70220126)
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| Project Period (FY) |
2009 – 2011
|
| Keywords | 超原子価ヨウ素 / 酸化 / ハイブリッド / 有機触媒 / ニトロキシルラジカル |
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| Research Abstract |
A novel hybrid-type organocatalyst having two deferent catalytic sites, 2, 2, 6, 6-tetramethyl-1-piperidinyloxyl(TEMPO) and iodobenzene sites, was developed and applied the oxidation of alcohols. The two catalytic sites were connected by ester bonds with phthalic acid as a linker. The reaction of primary alcohols with the catalyst in the presence of peracetic acid as a co-oxidant was smoothly proceeded to give the corresponding carboxylic acid in excellent yield.
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Research Products
(20 results)
