2011 Fiscal Year Final Research Report
Involvement of Cdk5 signaling in cough hypersensitivity during chronic cough
| Project/Area Number |
21590294
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
General pharmacology
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| Research Institution | Hoshi University |
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Principal Investigator |
KAMEI Junzo 星薬科大学, 薬学部, 教授 (40161236)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 中枢・末梢神経 / 慢性咳嗽 / テトロドトキシン(TTX) / TTX抵抗性Na^+チャネル |
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| Research Abstract |
The C-fiber sensitizing mechanisms have an important role in the enhancement of cough receptor sensitivity in chronic coughs. Cdk5-dependent factors are involved in these C-fiber-mediated cough sensitization.
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