2011 Fiscal Year Final Research Report
Comparative pathological study on H5N1 infection between humans and animals
| Project/Area Number |
21590449
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Experimental pathology
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| Research Institution | National Institute of Infectious Diseases |
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Principal Investigator |
ABE Kenji 国立感染症研究所, 感染病理部, 主任研究官 (60130415)
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| Project Period (FY) |
2009 – 2011
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| Keywords | インフルエンザ / H5N1 / 比較病理 / 感染動物 / 国際協力 |
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| Research Abstract |
We investigated autopsy cases of tigers and cats infected with H5N1.The animals had eaten fresh chicken or dead pigeon carcass infected with H5N1 and died caused by high fever and severe respiratory disorder. At necropsy, infected animals showed severe hemorrhagic lesion in a systemic organ. H5N1 related antigens was also detected in brain, lung and liver by an immunohistochemical method. Furthermore, a viral gene was isolated from lung tissue in infected animals and its showed high similarity to H5N1 isolated from a human patient in Thailand.
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Research Products
(17 results)
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[Journal Article] HCV 6a prevalence in guangdong province had the origin from Vietnam and recent dissemination to other regions of China2012
Author(s)
Yongshui Fu, Weibing Qin, Hong Cao, Ru Xu, Yi Tan, Teng Lu, Hongren Wang, Wangxia Tong, Xia Rong, Gang Li, Manqiong Yuan, Chunhua Li, Kenji Abe, Ling Lu
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Journal Title
Phylogeographic analyses
Volume: 7
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