2011 Fiscal Year Final Research Report
Analysis of the mechanism of Aichi virus replication complex formation.
| Project/Area Number |
21590514
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Virology
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| Research Institution | Fujita Health University |
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Principal Investigator |
SASAKI Jun 藤田保健衛生大学, 医学部, 講師 (70319268)
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| Project Period (FY) |
2009 – 2011
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| Keywords | アイチウイルス / 宿主因子 / ゲノム複製 / ACBD3 / PI4KB / PI4P |
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| Research Abstract |
Aichi virus is thought to be a causative agent of acute gastroenteritis in humans. Understanding the mechanism of the growth of pathogens is required for effective control of infectious diseases ; however, the mechanism of Aichi virus replication remains to be cleared. In this study, two host factors essential for Aichi virus replication were identified. The studies on other viruses report that these host proteins are involved in replication of the viruses. Findings in this study, together with the other studies, may lead to the development of drugs to control infection or growth of multiple viruses.
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