2011 Fiscal Year Final Research Report
Analysis of the mechanism and the tachycardia circuit of the atrial tachycardia originating from the atrioventricular annulus
| Project/Area Number |
21590904
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Kumamoto University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
OGAWA Hisao 熊本大学, 生命科学研究部, 教授 (50177135)
OKUMURA Ken 弘前大学, 医学研究科, 教授 (20185549)
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| Research Collaborator |
KOYAMA Junjiro 熊本大学, 医学部附属病院, 特任准教授
MORIHISA Kenji 熊本大学, 医学部附属病院, 特任助教
KANAZAWA Hisanori 熊本大学, 生命科学研究部, 大学院生
HOSHIYAMA Tadashi 熊本大学, 生命科学研究部, 大学院生
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| Project Period (FY) |
2009 – 2011
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| Keywords | 心房性頻拍 / 房室弁輪 / リエントリー / 房室結節 |
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| Research Abstract |
The purpose of this study was to elucidate the mechanism and the anatomical tachycardia circuit of the verapamil-sensitive atrial tachycardia, originating from the atrioventricular node. Entrainment and single extrastimulation technique, and radiofrequency technique revealed that the mechanism of this atrial tachycardia was due to reentry, which involves the calcium-channel dependent tissue in the reentry circuit. The slow conduction area, which is consisted of the calcium-channel dependent tissue, was shown to be extended outside the Koch's triangle.
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