2011 Fiscal Year Final Research Report
Molecular analysis of effects of HUB molecules in transcription factor network on cell differentiation
| Project/Area Number |
21591208
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Hematology
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| Research Institution | Kumamoto University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Keywords | 細胞分化 / 転写因子 / c-myb |
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| Research Abstract |
I established a new mouse line reporting the endogenious c-Myb protein level. By using these mice, it was evident that various types of hematopoietic progenitors and stem cells expressed c-Myb, some of which have never been reported before. Also, in hematopoietic stem cell population, c-Myb labeles around 90% of them, which presented futures different form c-Myb positive cells.
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