2011 Fiscal Year Final Research Report
Analysis of bacterial diversity in hospital environments and application for infection control using metagenomics
| Project/Area Number |
21591291
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Infectious disease medicine
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| Research Institution | Gunma University |
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Principal Investigator |
TOKUE Yutaka 群馬大学, 医学部, 准教授 (80292275)
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| Project Period (FY) |
2009 – 2011
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| Keywords | メタゲノミクス / 16S rRNA / 病院環境 / 感染対策 |
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| Research Abstract |
Sequencing of the 16S rRNA gene is recognized as an effective method for bacterial identification. For the control of hospital infections, we compared culture method and of bacterial diversity in the hospital environments where drug-resistant bacteria were isolated. Molecular biological analysis was more sensitive than culture method. This culture-independent analysis was able to detect some bacteria from sample of dried surface, so it was suggested to be available as an index of contaminated environment.
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[Journal Article] Criteria for safety evaluation of antimicrobial agents2011
Author(s)
Watanabe A, Tokue Y, Aoki N, Matsumoto T, Yanagihara K, Higa F, Tsuge H, Nagashima M, Matsuoka H, Sasagawa Y, Matsumoto M, Fujimaki K, Taguchi K, Ariyasu M, Yamamoto N, Kunii O, Shiba K
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Journal Title
J Infect Chemother
Volume: 17
Pages: 47-139
Peer Reviewed
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[Journal Article] Association between Mycobacterial genotypes and disease progression in Mycobacterium avium pulmonary infection2009
Author(s)
Kikuchi T, Watanabe A, Gomi K, Sakakibara T, Nishimori K, Daito H, Fujimura S, Tazawa R, Inoue A, Ebina M, Tokue Y, Kaku M, Nukiwa T
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Journal Title
Thorax
Volume: 64
Pages: 901-907
Peer Reviewed
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