2011 Fiscal Year Final Research Report
Pathogenesis and pathophysiology of pediatric multiple sclerosis and acute disseminated encephalomyelitis
| Project/Area Number |
21591326
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Pediatrics
|
|---|
| Research Institution | Kyushu University |
|---|
Principal Investigator |
KIRA Ryutaro 九州大学, 大学病院, 特別教員 (70304805)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
TORISU Hiroyuki 九州大学, 大学病院, 助教 (10398076)
SANEFUJI Masafumi 九州大学, 大学病院, 助教 (50467940)
ISHIZAKI Yoshito 九州大学, 大学病院, 助教 (20572944)
LEE Sooyoung 九州大学, 大学病院, 助教 (10529796)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
MIZUGUCHI Masashi 東京大学, 医学系研究科, 教授 (20209753)
ICHIYAMA Takashi 山口大学, 医学系研究科, 教授 (20263767)
MAEGAKI Yoshihiro 鳥取大学, 医学部, 准教授 (80252849)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Keywords | 小児神経学 |
|---|
| Research Abstract |
Acute disseminate encephalomyelitis(ADEM) and pediatricmultiple sclerosis(MS) are very rare diseases. The pathogenesis and pathophysiology remain to be fully clarified. To find their diagnostic markers, we delineated the clinical features of the epidemiological backgrounds ; signs and symptoms ; laboratory, neurophysiological, and magnetic resonance imaging(MRI) findings ; treatments ; and prognoses of these diseases, based on the definition proposed by the International Pediatric MS Study Group(2007). In addition, we performed genetic association studies in ADEM patients and controls. The results revealed several characteristics of each disease.
|
-
[Journal Article] Clinical and MRI characteristics of acute encephalopathy in congenital adrenal hyperplasia2011
Author(s)
Lee S, Sanefuji, M, Watanabe K, Uematsu A, Torisu, H, Baba H, Kira, R, Takada Y, Ishizaki Y, Toyoshima M, Aragaki F, Hata D, Hara T
-
Journal Title
J Neurol Sci
Volume: 306
Pages: 91-93
DOI
-
-
[Journal Article] Parental age and child growth and development2011
Author(s)
Iwayama M, Kira, R, Kinukawa N, Sakai Y, Torisu, H, Sanefuji, M, Ishizaki Y, Nose Y, Matsumoto T, Hara T
-
Journal Title
child health check蓉p data
Volume: 53
Pages: 709-714
DOI
-
-
-
[Journal Article] Genetic susceptibility to febrile seizures2010
Author(s)
Kira, R, Ishizaki Y, Torisu, H, Sanefu j i, M, Takemoto M, Sakamoto K, Matsumoto S, Yamaguchi Y, Yukaya N, Sakai Y, Gondo K, Hara T
-
Journal Title
Case幼ontrol association studies
Volume: 32
Pages: 57-63
DOI
-
[Journal Article] PDl as a common candidate susceptibility gene of subacute sclerosing panencephalitis2010
Author(s)
Ishizaki Y, Yukaya N, Kusuhara K, Kira, R, Torisu, H, Ihara K, Sakai Y, Sanefuji, M, Pipo-Deveza JR, Silao CL, Sanchez BC, Lukban MB, Salonga AM, Hara T
-
Journal Title
Hum Genet
Volume: 127
Pages: 411-9
DOI
-
-
-
-
-
-
-
-
-
-
-
-
-
