2011 Fiscal Year Final Research Report
The identification of causative genes of hereditary skin diseases
| Project/Area Number |
21591426
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Dermatology
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| Research Institution | Hokkaido University |
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Principal Investigator |
ARITA Ken 北海道大学, 大学院・医学研究科, 助教 (50374434)
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| Co-Investigator(Kenkyū-buntansha) |
AKIYAMA Masashi 北海道大学, 大学院・医学研究科, 准教授 (60222551)
NOMURA Toshifumi 北海道大学, 大学院・医学研究科, 助教 (50399911)
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| Project Period (FY) |
2009 – 2011
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| Keywords | Michelin tire baby syndrome / 連鎖解析 / 遺伝子候補領域 |
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| Research Abstract |
The cause of the inherited skin diseases has been elucidated gradually by means of advanced skills of genetic analyses, however, for a lot of the inherited skin diseases the causative genes has left unknown. We focused on Michelin tire baby syndrome, which is an autosomal recessive congenital skin disease, and investigated the causative gene using linkage analyses. We collected DNA samples from three families of Michelin tire baby syndrome, and we identified a DNA locus D7S2480-D7S515 as a candidate region of the causative gene. We hope a further progress will be made based upon this result.
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Research Products
(1 results)
