2011 Fiscal Year Final Research Report
Effects on metabolism and cognitive functions by hypnotics induced slow wave sleep modulation in healthy young male volunteers
| Project/Area Number |
21591493
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Psychiatric science
|
|---|
| Research Institution | Kitasato University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
KUMAGAI Yuji 北里大学, 医学部, 教授 (40215017)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Keywords | 精神薬理学 |
|---|
| Research Abstract |
Slow wave sleep(deep sleep) is known to be important to maintain glucose tolerance, i. e. to avoid diabetes in future. It is also known that certain hypnotic increases or decreases slow wave sleep. To clear whether hypnotics induced slow wave modulations have equivalent effect on glucose tolerance as that induced by behavior or sleep deprivation, we investigated glucose tolerance in the morning preceded by nighttime hypnotic administration. It was suggested that hypnotic administration improves glucose tolerance. However, relation between slow wave modulation and glucose tolerance was not cleared. We will continue this study to add participants.
|
