2011 Fiscal Year Final Research Report
Assessment of central nervous system function through autonomic nervous system in Alzheimer's disease
| Project/Area Number |
21591510
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Psychiatric science
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| Research Institution | Nagoya University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
SUZUKI Yusuke 名古屋大学, 大学院・医学系研究科, 講師 (90378167)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 認知症 / 老化 / ストレス |
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| Research Abstract |
In animal experiment the acute administration of cholinesterase inhibitor(ChEI) activated the sympathetic nervous system, while the chronic administration affected the parasympathetic nervous system.
In the clinical study, we found the negative correlation between depressive mood and the activity of sympathetic nervous system in AD subjects.
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