• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2012 Fiscal Year Final Research Report

Establishment of MRI-guided planning in high-dose-rate brachytherapyof prostate cancer

Research Project

  • PDF
Project/Area Number 21591582
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Radiation science
Research InstitutionKawasaki Medical School

Principal Investigator

TAMADA Tsutomu  川崎医科大学, 医学部, 准教授 (40278932)

Co-Investigator(Kenkyū-buntansha) ITO Katsuyoshi  川崎医科大学, 医学部, 教授 (00274168)
YAMASHITA Takenori  川崎医科大学, 医学部, 講師 (30299200)
Co-Investigator(Renkei-kenkyūsha) SONE Teruki  川崎医科大学, 医学部, 教授 (90179383)
JO Yoshimasa  川崎医科大学, 医学部, 講師 (40319968)
Project Period (FY) 2009 – 2012
Keywords前立腺癌 / 核磁気共鳴画像 / MRI
Research Abstract

In our studies using multiparametric prostate MR imaging, the tumor detectability of prostate cancer before radiotherapy (high-dose-rate brachytherapy (HDR-BT)), the change of MR findings after HDR-BT and the detectability of locally recurrent prostate cancer after HDR-BT were investigated. As the results, multiparametric MRI showed the high detectability for a significant cancer with the treatment intervention. In addition, after radiotherapy, the MR findings in T2-weighted imaging such as zonal indistinctness and diffuse reduction of the signal intensity in the gland interfered with the diagnosis of recurrent tumor. Furthermore, our results indicated that a multiparametric MRI protocol that includes diffusion-weighted imaging provides a sensitive method to detect local recurrence after HDR brachytherapy.

  • Research Products

    (9 results)

All 2013 2012 2011 2010 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (5 results) Remarks (1 results)

  • [Journal Article] Diffusion-weighted MRI and its role in prostate cancer2013

    • Author(s)
      Tamada T, Sone T, Jo Y, Yamamoto A, Ito K
    • Journal Title

      NMR Biomed

      Volume: (印刷中)

    • DOI

      doi:10.1002/nbm.2956.

    • Peer Reviewed
  • [Journal Article] Prostate cancer detection in patients with total serum prostate-specific antigen levels of 4-10 ng/mL: diagnostic efficacy of diffusion-weighted imaging, dynamic contrast-enhanced MRI, and T2-weighted imaging.2011

    • Author(s)
      Tamada T, Sone T, Higashi H, Jo Y, Yamamoto A, Kanki A, Ito K.
    • Journal Title

      AJR Am J Roentgenol.

      Volume: 197 Pages: 664-670

    • DOI

      doi:10.2214/AJR.10.5923

    • Peer Reviewed
  • [Journal Article] Locally recurrent prostate cancer after high-dose-rate brachytherapy: the value of diffusion-weighted imaging, dynamic contrast-enhanced MRI, and T2-weighted imaging in localizing tumors.2011

    • Author(s)
      Tamada T, Sone T, Jo Y, Hiratsuka J,Higaki A, Higashi H, Ito K
    • Journal Title

      AJR Am J Roentgenol

      Volume: 197 Pages: 408-414

    • DOI

      doi:10.2214/AJR.10.5772.

    • Peer Reviewed
  • [Presentation] PROSTATE CANCER DETECTION IN PATIENTS WITH TOTAL SERUM PROSTATE-SPECIFIC ANTIGEN LEVELS BETWEEN 4 AND 10 NG/ML: DIAGNOSTIC EFFICACY OF MULTI-PARAMETRIC MR IMAGING2012

    • Author(s)
      Tsutomu Tamada, Hiroki Higashi,Teruki Sone, Yoshimasa Jo, Atsushi Higaki, Akihiko Kanki, Akira Yamamoto, and Katsuyoshi Ito.
    • Organizer
      ISMRM
    • Place of Presentation
      Melbourne オーストリア
    • Year and Date
      20120505-11
  • [Presentation] 前立腺癌における高線量率組織内照射後の局所再発:MultiparametricMRIによる腫瘍検出能に関する検討2012

    • Author(s)
      玉田勉、常義政、曽根照喜、東浩樹、原稜英、永井敦、伊東克能.
    • Organizer
      日本泌尿器科学会総会
    • Place of Presentation
      横浜
    • Year and Date
      20120421-24
  • [Presentation] Prostate cancer detection in patients with total serum prostate-specific antigen levels of4-10 ng/ml: diagnostic efficacy of diffusion-weighted imaging, dynamic contrast-enhanced MRI and T2-weighted imaging2011

    • Author(s)
      Tsutomu Tamada, Akira Yamamoto, Yoshimasa Jo, Hiroki Higashi, and Katsuyoshi Ito.
    • Organizer
      ESUR-SUR
    • Place of Presentation
      Dubrovnik クロアチア
    • Year and Date
      20111013-16
  • [Presentation] MR Diagnosis in Prostate Cancer Detection: The Spectrum of Imaging Findings on Pre and Post Therapy2010

    • Author(s)
      Tsutomu Tamada, Katsuyoshi Ito, Hiroki Higashi, Daigo Tanimoto, Naoto Egashira, Fuyuki Tanaka, Tomohiro Sato, Akihiko Kanki, Atsushi Higaki, Teruyuki Torigoe, and Yasufumi Noda.
    • Organizer
      RSNA
    • Place of Presentation
      Chicago アメリカ
    • Year and Date
      20101128-1203
  • [Presentation] Gray zone PSA症例の前立腺癌の検出におけるMRIの有用性2010

    • Author(s)
      玉田勉、常義政、曽根照喜、東浩樹、原稜英、永井敦、伊東克能.
    • Organizer
      日本泌尿器科学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      20100421-24
  • [Remarks] 川崎医科大学放射線医学(画像診断1)のHP,今回の研究結果の一部を掲載している。

    • URL

      http://www.kawasaki-m.ac.jp/diag-radiology/

URL: 

Published: 2014-08-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi