2011 Fiscal Year Final Research Report
Development of novel copper-64 labeled antibodies.
| Project/Area Number |
21591593
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Gunma University |
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Principal Investigator |
TOMINAGA Hideyuki 群馬大学, 大学院・医学系研究科, 寄附講座教員 (00393348)
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| Co-Investigator(Kenkyū-buntansha) |
ENDO Keigo 京都医療科学大学, 医療科学部, 学長 (10115800)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 銅-64 / PET / 抗体医薬 / 新規キレート / サイクロトロン / 放射性医薬品 / 診断薬 / 院内製剤 |
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| Research Abstract |
In Gunma University, I was enabled in producing copper-64 which was a positron emitter by medical cyclotron. We stably synthesized SarAr cheleter, Sarcophagine, 3, 6, 10, 13, 16, 19-hexaazabicycle[6. 6. 6]-eicosane-1, 8-diamine, as novel chelator for copper-64 labeling. We hope that the application by various labeling antibodies comes to be a new diagnosis.
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