2011 Fiscal Year Final Research Report
Trial of determining prognostic factors in breast cancer patients
Project/Area Number |
21591660
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
General surgery
|
Research Institution | University of Toyama |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
TSUKADA Kazuhiro 富山大学, 大学院・医学薬学研究部(医学), 教授 (90171967)
|
Co-Investigator(Renkei-kenkyūsha) |
SHIMADA Yutaka 富山大学, 大学院・医学薬学研究部(医学), 准教授 (30216072)
|
Project Period (FY) |
2009 – 2011
|
Keywords | 乳腺外科学 / iPS細胞 / Nanog / KLF4 |
Research Abstract |
The aim of present study, is to examine the relationship between the expression of iPS cell inducing factors(Oct4、Sox2、Klf-4、c-Myc、Nanog) and the prognosis of the breast cancer patients. Strong expression of NANOG was an indicator of a poor prognosis for breast cancer patients, while KLF4 was a favorable prognostic indicator.
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