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2011 Fiscal Year Final Research Report

A mouse model of lung tissue transplantation with biocompatible scaffold materials

Research Project

  • PDF
Project/Area Number 21591825
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionKeio University

Principal Investigator

SAWAFUJI Makoto  慶應義塾大学, 医学部, 講師(非常勤) (10226079)

Co-Investigator(Kenkyū-buntansha) WATANABE Masazumi  慶應義塾大学, 医学部, 教授 (90201227)
IZUMI Yotaro  慶應義塾大学, 医学部, 講師 (90245506)
KOHNO Mitsutomo  慶應義塾大学, 医学部, 講師 (10276272)
Project Period (FY) 2009 – 2011
Keywords呼吸器外科学
Research Abstract

We developed a mouse model of lung tissue transplantation using biocompatible scaffold materials. Fragments of fetal lung tissue taking from GFP mice were infused with biocompatible materials into the lungs of wild type recipient mice. Grafts expressing GFP were observed for three days after transplantation.

  • Research Products

    (5 results)

All 2012 2011 2009

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (2 results)

  • [Journal Article] Mitigation of occult lung injury by pneumonectomy via minithoracotomy in mice2012

    • Author(s)
      Kohno M, Watanabe M, Izumi Y, Tasaka S, Kitagawa Y, Maruyama I, Kobayashi K
    • Journal Title

      Thorac Cardiovasc Surg

      Volume: 60(2) Pages: 124-30

    • Peer Reviewed
  • [Journal Article] Treatment of intractable interstitial lung injury with alemtuzumab after lung transplantation2011

    • Author(s)
      Kohno M, Perch M, Andersen E, Carlsen J, Andersen CB, Iversen M
    • Journal Title

      Transplant Proc

      Volume: 43(5) Pages: 1868-70

    • Peer Reviewed
  • [Journal Article] Airway administration of dexamethasone, 3'-5'-cyclic adenosine monophosphate, and isobutylmethylxanthine facilitates compensatory lung growth in adult mice2011

    • Author(s)
      Takahashi Y, Izumi Y, Kohno M, Kawamura M, Ikeda E, Nomori H.
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol

      Volume: 300(3) Pages: L453-61

    • Peer Reviewed
  • [Presentation] ラット肺瘻モデルにおけるフィブリン糊肺実質内充填による肺瘻閉鎖2009

    • Author(s)
      江間俊哉、河野光智、儀賀理暁、田島敦志、泉陽太郎、渡辺真純、川村雅文、堀之内宏久、小林紘一
    • Organizer
      第26回日本呼吸器外科学会総会
    • Year and Date
      20090514-15
  • [Presentation] 生体適合性ゲル化物質の肺実質内充填による肺瘻閉鎖の実験的検討2009

    • Author(s)
      河野光智、江間俊哉、儀賀理暁、泉陽太郎、渡辺真純、堀之内宏久、川村雅文、小林紘一
    • Organizer
      第26回日本呼吸器外科学会総会
    • Year and Date
      20090514-15

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Published: 2013-07-31  

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