2011 Fiscal Year Final Research Report
New interventional approach using LED plus lens for treatment of malignant mesothelioma
| Project/Area Number |
21591826
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Thoracic surgery
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| Research Institution | Tokyo Medical University |
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Principal Investigator |
USUDA Jitsuo 東京医科大学, 医学部, 准教授 (60338803)
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| Co-Investigator(Kenkyū-buntansha) |
IKEDA Norihiko 東京医科大学, 外科学, 教授 (70246205)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 光線力学治療 / 胸膜中皮腫 / 発光ダイオード |
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| Research Abstract |
It was able to gather rays of light from LED using lens and photodynamic therapy using LED plus lens killed malignant mesothelioma cells. Moreover, combination treatment, consisting of pemetrexed followed by NPe6-PDT, should be further investigated as a new treatment modality for malignant pleural mesothelioma. In the future, this combination treatment, PDT using LED plus lens and pemetrexed, may contribute to a reduction in local recurrence and a prolonged survival period in patients with malignant pleural mesothelioma.
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[Journal Article] Outcome of photodynamic therapy using NPe6 for bronchogenic carcinomas in central airways> 1.0cm in diameter2010
Author(s)
Usuda J., Ichinose S., Ishizumi T., Hayashi H., Ohtani K., Maehara S., Ono S., Honda H., Kajiwara N., Uchida O., Tsutsui H., Ohira T., Kato H., Ikeda N.
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Journal Title
Clin Cancer Res
Volume: 16
Pages: 2198-2204
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[Journal Article] Management of multiple primary lung cancer in patients with centrally located early cancer lesions2010
Author(s)
Usuda J., Ichinose S., Ishizumi T., Hayashi H., Hayashi H., Ohtani K., Maehara S., Ono S., Kajiwara N., Uchida O., Tsutsui H., Ohira T., Kato H., Ikeda N.
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Journal Title
J Thorac Oncol
Volume: 5
Pages: 62-68
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[Journal Article] Breast cancer resistant protein(BCRP) is a molecular determinant of the outcome of photodynamic therapy(PDT) for centrally located early lung cancer2010
Author(s)
Usuda J., Tsunoda Y., Ichinose S., Ishizumi T., Ohtani K., Maehara S., Ono S., Tsutsui H., Ohira T., Okunaka T., Furukawa K., Sugimoto Y., Kato H., Ikeda N.
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Journal Title
Lung Cancer
Volume: 67
Pages: 198-204
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