2011 Fiscal Year Final Research Report
Investigation of new treatment target genes for GBM based on classification of GBM stem cells
| Project/Area Number |
21591874
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Kumamoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KURATSU Jun-ichi 熊本大学, 大学院・生命科学研究部, 教授 (20145296)
NAKAMURA Hideo 熊本大学, 医学部附属病院, 助教 (30359963)
MAKINO Keishi 熊本大学, 大学院・生命科学研究部, 助教 (90381011)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 癌幹細胞 / 神経膠芽腫 / 培養 / 治療 |
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| Research Abstract |
Seven of GBM stem cell from human GBM tissues were established. Classification of GBM stem cells is going now. A candidate of GBM stem cell marker was identified, which highly expressed in perivasucular area and invasion front where GBM stem cells and niche exist. Characterization of this gene for GBM stem cells is going on.
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Research Products
(32 results)
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[Journal Article] Antitumor effect of humanized anti-interleukin-6 receptor antibody(tocilizumab) on glioma cell proliferation2009
Author(s)
Kudo M, Jono H, Shinriki S, Yano S, Nakamura H, Makino K, Hide T, Muta D, Ueda M, Ota K, Ando Y, Kuratsu J
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Journal Title
J Neurosurg
Volume: 111
Pages: 219-225
Peer Reviewed
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