2011 Fiscal Year Final Research Report
A comparative study of the bone forming ability of surface-treated porous titanium materials
| Project/Area Number |
21591898
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Kyoto University |
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Principal Investigator |
NEO Masashi 京都大学, 医学研究科, 准教授 (80311736)
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| Co-Investigator(Renkei-kenkyūsha) |
TAKEMOTO Mitsuru 京都大学, 医学研究科, 助教 (00456873)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 生体活性 / チタン / 脊椎 / インプラント / 固定術 / 骨誘導 |
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| Research Abstract |
We investigated the effect of the surface treatment on the bone forming abilities of porous titanium implant in the long term. Three types of surface treatments were applied :(a) hydroxyapatite coating(HA),(b) alkali, hot water, and heat treatment(AW), and(c) alkali, dilute HCl, hot water, and heat treatment(HCl). We then examined the amount of bone formation within the materials implanted in the femoral condyles of Japanese white rabbits at 6, 12, 26, 52, and 104 weeks. The results showed that the bone ingrowth in AW and HCl was significantly higher than in HA after 52 and after 12 weeks, respectively.
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