2011 Fiscal Year Final Research Report

Basic science technology study of new revision total hip arthroplasty using a fusion protein and the nanowire processing

Research Project

Project/Area Number	21591923
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Orthopaedic surgery
Research Institution	Kitasato University
Principal Investigator	NARUSE Kouji 北里大学, 医学部, 講師 (60276087)
Co-Investigator(Kenkyū-buntansha)	ITOMAN Moritoshi 北里大学, 名誉教授 (70104528) URABE Ken 北里大学, 医学部, 准教授 (90284489) MATSUSHITA Osamu 北里大学, 医学部, 教授 (00209537)
Project Period (FY)	2009 – 2011
Keywords	材料工学・処理 / 組織移植 / 融合タンパク
Research Abstract	In this study we aimed to develop a new reconstruction technique for widespread bone defects that occur during revision and second revision total hip arthroplasty. We strived to significantly improve joint function restoration techniques that are currently based on existing bone allograft. prosthesis composite materials by using hormone-collagen binding domain and growth factor. collagen binding domain as molecular biological tools, as well as metal. plated nanowire processing technology as a medical engineering tool. Our study revealed that basic fibroblast growth factors. collagen binding domain were useful in the development of the new reconstruction technique.

(3 results)