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2011 Fiscal Year Final Research Report

Analysis of calcifying panoparticles in joint diseases

Research Project

  • PDF
Project/Area Number 21591950
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthopaedic surgery
Research InstitutionNagasaki University

Principal Investigator

TSURUMOTO Toshiyuki  長崎大学, 大学院・医歯薬学総合研究科, 教授 (60304937)

Co-Investigator(Kenkyū-buntansha) YONEKURA Akihiko  長崎大学, 大学院・医歯薬学総合研究科, 助教 (20380850)
KAJIYAMA Shiro  長崎大学, 大学院・医歯薬学総合研究科, 助教 (90418822)
Research Collaborator ANDREI P. sommer  
Project Period (FY) 2009 – 2011
Keywords関節炎 / 変形性関節症 / 関節リウマチ / 外傷後関節炎 / 石灰化
Research Abstract

It has been reported that" calcifying nanoparticles(CNPs)" induce local inflammation and cell death around them in the human bodies. This study showed that synovial fluid of patients who suffered from osteoarthritis, rheumatoid arthritis and post-traumatic arthritis contained nanoparticles those sizes were less than 1000nm. The size of nanoparticles from osteoarthritis was less than 100nm, and therefore they were thought to be" calcifying nanoparticles" and they could play significant roles in calcification and ossification around the osteoarthritic joints.

  • Research Products

    (1 results)

All 2009

All Presentation (1 results)

  • [Presentation] 変形性関節症患者の関節液におけるbiological nanoparticleの存在意義について2009

    • Author(s)
      弦本敏行、進藤裕幸
    • Organizer
      第53回日本リウマチ学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2009-04-23

URL: 

Published: 2013-07-31  

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