2011 Fiscal Year Final Research Report
Rhythm formation of fetal brain function and effect of maternal environmental stress
| Project/Area Number |
21592103
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | University of Miyazaki |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TATSUMOTO Shin 宮崎大学, 教育文化学部, 准教授 (50279965)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 胎児脳機能 / active and inactive state / リズム形成 / 中大脳動脈血流速度 / 神経学的発達 / 心理学的検査 |
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| Research Abstract |
Based on the observation of fetal heart rate pattern, two different states of brain functions are differentiated. These 2 different states appear one after another with some rhythmic cycle. This phenomenon is considered to represent the functional changes of the fetal brain.
We have revealed that normally developing fetus obtains the rhythmic cycle at 33 weeks of gestation whereas the intrauterine growth restricted fetus delays it significantly.(fig. 1)
The middle cerebral artery Doppler velocimetry during active state varies more than that of during non active state significantly.(fig. 2)
We finished the tests of rhythm formation on 143 fetuses and will completed the developmental psychological examination at the age of 3.
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