2011 Fiscal Year Final Research Report
Apotosis expressed in the experimental middle ear cholesteatoma
| Project/Area Number |
21592158
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Showa University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Keywords | 中耳真珠腫 / 実験モデル / アポトーシス |
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| Research Abstract |
Middle ear cholesteatoma is an intractable disease which has strong epithelial proliferation potency and destroys the surrounding organs. The pathogenesis of cholesteatoma is still controversial, and the recurrence rate is high. This study demonstrates apotosis plays some roles in dysfunction of the epithelial proliferation, using experimental animal models.
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