2011 Fiscal Year Final Research Report
Role of D-amino acid-containing proteins in the development of diabetic retinopathy
Project/Area Number |
21592216
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Ophthalmology
|
Research Institution | University of Tsukuba |
Principal Investigator |
KAJI Yuichi 筑波大学, 医学医療系, 准教授 (50361332)
|
Project Period (FY) |
2009 – 2011
|
Keywords | 眼生化学 / 分子生物学 |
Research Abstract |
First, we have shown that accumulation of D-amino acid-containing proteins in the basement membrane of the cornea induces diabetic keratopathy. Second, we have found increased concentration of D-amino acid-containing proteins in the vitreous fluid of diabetic retinopathy. Finally, we have developed a photodynamic therapy for corneal dystrophy using in vitro model.
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Research Products
(26 results)