2011 Fiscal Year Final Research Report
Research on the development of the new medical treatment and its clinical use in adenoviral ocular infection
| Project/Area Number |
21592269
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Ophthalmology
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| Research Institution | Fukuoka University |
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Principal Investigator |
UCHIO Eiichi 福岡大学, 医学部, 教授 (70232840)
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| Project Period (FY) |
2009 – 2011
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| Keywords | アデノウイルス / 抗ウイルス薬 / 逆転写酵素阻害薬 / 抗HIV薬 / レセプター阻害薬 |
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| Research Abstract |
We evaluated anti-adenoviral activity of candidate agents in vitro. Among interferons, both interferon beta and gamma showed significant antiviral effect on adenovirus. LL-37, an antimicrobial peptide, also had antiadenoviral activity on all types except for type 4.These results suggest that these agents might be used safely for treatment of human adenoviral conjunctivitis in the near future.
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[Journal Article] アデノウイルス結膜炎院内感染対策ガイドライン2009
Author(s)
塩田洋, 大野重昭, 青木功喜, 安積淳, 石子博昭, 井上幸次, 薄井紀夫, 内尾英一, 金子久俊, 熊倉重人, 田川義継, 谷藤泰寛, 中川尚, 日隈陸太郎, 山崎修道, 横井則彦
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Journal Title
日本眼科学会雑誌
Volume: 113
Pages: 25-46
Peer Reviewed
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