2011 Fiscal Year Final Research Report
Long term efforts on Growth and Immunological balances from Immunosuppressant in children who underwent Living Donor Liver Transplantation at the age under one year old.
| Project/Area Number |
21592279
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Pediatric surgery
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
OKAJIMA Hideaki 京都府立医科大学, 医学研究科, 准教授 (20308604)
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| Co-Investigator(Kenkyū-buntansha) |
INOMATA Yukihiro 熊本大学, 医学薬学研究科, 教授 (50193628)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 先天性消化器疾患 |
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| Research Abstract |
Total of twenty children who received liver transplantation at the age with less than one year old and followed up more than five years were studied of physical and immunological influences from immunosuppressant with calcinulin inhibitors. Growth retardation appeared before transplantation and improved after transplantation. Immunological balances that was evaluated with Th1/Th2 showed normal pattern after liver transplantation in all the children who were administered with tacrolimus.
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