2011 Fiscal Year Final Research Report
Identification of urinary biomarkers to predict onset of acute kidney injury with proteomic analysis
| Project/Area Number |
21592310
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Emergency medicine
|
|---|
| Research Institution | Yamaguchi University |
|---|
Principal Investigator |
KASAOKA Shunji 山口大学, 大学院・医学系研究科, 准教授 (90243667)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
MAEKAWA Tsuyoshi 山口大学, 大学院・医学系研究科, 教授 (60034972)
IZUMI Tomonori 山口大学, 大学院・医学系研究科, 准教授 (00261694)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Keywords | 急性腎障害 / 尿中バイオマーカー / プロテオーム解析 |
|---|
| Research Abstract |
We investigated the usefulness of urinary biomarker for early diagnosis of acute kidney injury(AKI). Our study suggested that urinary NGAL might be more useful for early diagnosis of AKI than urinary L-FABP. In addition, 368 kinds of proteins by proteomic analysis of urine have been detected, and it is to be expected to establish a new biomarker.
|
