2011 Fiscal Year Final Research Report
Morphological analysis of cementogenesis using a newly identified cementoblast specific marker
| Project/Area Number |
21592322
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MAEDA Takeyasu 新潟大学, 医歯学系, 教授 (40183941)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 歯根形成 / アクアポリン / セメント質 / 顕微解剖学 / 免疫組織化学 |
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| Research Abstract |
We demonstrated the expression of aquaporin during cementgenesis. Cells on the developing root surface expressed aquaporin in rat molars during acellular cementgenesis. We immuno-histochemicaly identified these cells as cementblasts. The expression of aquaporin was observed on the cells on the interface between periodontal ligament and alveolar bone during alveolar bone development. These cells showed the different shapes from cementoblasts and possessed wing-like projections. These results suggest that aquapolin plays an important role during the development of periodontal tissue.
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