2011 Fiscal Year Final Research Report
Remineralization strategy for enamel subsurface lesions using bleaching therapy
| Project/Area Number |
21592436
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Kanagawa Dental College |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
TERANAKA Toshio 神奈川歯科大学, 歯学部, 教授 (60104460)
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| Project Period (FY) |
2009 – 2011
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| Keywords | エナメル質表層下脱灰病巣 / ブリーチング / 唾液タンパク質 / 再石灰化 |
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| Research Abstract |
Salivary proteins reacted with 30% H_2O_2, resulting in fragmentation of certain proteins. Also, we detected in-office bleaching agent in their capacity to remove human salivary protein components penetrated into the enamel subsurface lesions. Furthermore, western blotting with antibody against serum statherin indicated that antibody response of statherin in the lesions was undetectable after the in-office bleaching. These results indicate that bleaching will be useful for advancing of enamel remineralization.
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