2011 Fiscal Year Final Research Report
The various clinical applicability of cultured oral epithelial cells sheet on amniotic membrane
| Project/Area Number |
21592535
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Surgical dentistry
|
|---|
| Research Institution | Kyoto Prefectural University of Medicine |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
YAMAMOTO Toshiro 京都府立医科大学, 医学研究科・歯科口腔科学, 講師 (40347472)
AMEMIYA Takeshi 京都府立医科大学, 医学研究科・歯科口腔科学, 助教 (90398389)
AKAMATSU Yuki 京都府立医科大学, 医学研究科・歯科口腔科学, 助教 (40580733)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Keywords | 口腔外科一般(含病態検査学) |
|---|
| Research Abstract |
Autologous oral mucosal epithelial sheets, which were cultivated on amniotic membrane, were used for the transplantation of oral mucosa after oral surgery(9 cases : mucocele ; oral leukoplakia ; pleomorphic adenoma ; lip neoplasm ; and fibroma of buccal mucosa). In 7 of these cases, a favorable post-transplant course was obtained with reproduced oral mucosa without abnormalities at the transplantation site. On the other hand, transplant approaches were not applicable in the remaining 2 cases, in which the diseased portion was removed, involving a substantial loss, suggesting the necessity of examining the appropriate selection of patients and surgical procedures for transplantation.
|
