2011 Fiscal Year Final Research Report
New approach to the mechanism of the pain by orthodontic tooth movement
| Project/Area Number |
21592596
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAMIOKA Hiroshi 岡山大学, 大学院・医歯薬学総合研究科, 准教授 (80253219)
YAMASHIRO Takashi 岡山大学, 大学院・医歯薬学総合研究科, 教授 (70294428)
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| Project Period (FY) |
2009 – 2011
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| Keywords | グリア / 痛み / 歯の移動 / 共焦点顕微鏡 / 組織学的形態計測 |
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| Research Abstract |
Orthodontic tooth movement evokes a pain. As for the past research to the mechanism of the pain, the focus has been placed on neural cells. This research newly focused on glial cells surrounding neurons, and searched how glial cells involved in the development of the pain by orthodontic tooth movement. This research revealed not only temporal distribution of activated glial cells but also the involvement of CGRP and VR1 in central nervous system during orthodontic tooth movement.
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