2011 Fiscal Year Final Research Report
Interpretation for diffusion weighted MRI image by computer simulation with brain blood vessel model
| Project/Area Number |
21613005
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Non-invasive neuroimaging
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| Research Institution | Akita Prefectural University |
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Principal Investigator |
CHEN Guoyue 秋田県立大学, システム科学技術学部, 教授 (20282014)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Kazuhiro 秋田県立脳血管研究センター(研究部門), 放射線医学研究部, 主任研究員 (10312638)
MIZUSAWA Shigenori 秋田県立脳血管研究センター(研究部門), 循環器内科学研究部, 主任研究員 (80360361)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 脳機能画像 / 拡散強調画像 / 脳血管モデル / シミュレーション / 脳血流(CBF) |
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| Research Abstract |
We performed computer simulation to reveal a relation between cerebral blood volume(CBV) and diffusion weighted magnetic resonance image. Apparent diffusion coefficient(ADC) calculated from typical single refocused pulsed-gradient spin-echo sequence was underestimated by magnetic susceptibility of vascular networks especially from increase number of small vessels in brain. We confirm the influence of ADC can be reduced by using twice-refocused spin-echo sequence.
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