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2011 Fiscal Year Final Research Report

Autonomous flowing tube system for chemical solution propelled by its self-energy

Research Project

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Project/Area Number 21650041
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Perception information processing/Intelligent robotics
Research InstitutionTokyo Medical and Dental University

Principal Investigator

MITSUBAYASHI Kohji  東京医科歯科大学, 生体材料工学研究所, 教授 (40307236)

Co-Investigator(Kenkyū-buntansha) HIROYUKI Kudo  東京医科歯科大学, 生体材料工学研究所, 講師 (70329118)
MIYAJIMA Kumiko  東京医科歯科大学, 生体材料工学研究所, 技術職員 (10516298)
TAKAHASHI Daishi  東京医科歯科大学, 生体材料工学研究所, 特任助教 (20549943)
SAITO Hirokazu  東京工業高等専門学校, 機械工学科, 准教授 (00205668)
Project Period (FY) 2009 – 2011
Keywords化学エネルギー / 酵素 / 反応セル / グルコース / 隔膜 / 減圧 / チューブ / 送液
Research Abstract

Novel chemo-mechanical energy conversion device for glucose as blood sugar was constructed using a glucose oxidase immobilized membrane. And an autonomous flowing system for glucose solution was fabricated by applying the device to a reaction cell with some valves. As the results, the novel energy conversion device indicated a decompression behavior which has a linear relationship with the concentration of glucose. The flowing system streamed with glucose solution(approx. 25μl/min) by its self-energy successfully.

  • Research Products

    (14 results)

All 2011 2010 2009

All Journal Article (6 results) Presentation (7 results) Book (1 results)

  • [Journal Article] Biomedical soft contact-lens sensor for in-situ ocular biomonitoring of tear contents2011

    • Author(s)
      M. X. Chu, D. Takahashi, T. Arakawa, H. Kudo, K. Sano, S. Sawada, Y. Iwasaki, K. Akiyoshi, M. Mochizuki, K. Mitsubayashi
    • Journal Title

      Biomedical Microdevices

      Volume: 13 Pages: 306-611

  • [Journal Article] Soft contact lens biosensor for in situ monitoring of tear glucose as non-invasive blood sugar assessment2011

    • Author(s)
      M. X. Chu, K. Miyajima, D. Takahashi, T. Arakawa, K. Sano, S. Sawada, H. Kudo, Y. Iwasaki, K. Akiyoshi, M. Mochizuki, K. Mitsubayashi
    • Journal Title

      Talanta

      Volume: 83 Pages: 960-965

  • [Journal Article] An autonomous drug-release system based on chemo-mechanical energy conversion"Organic Engine"for feedback control of blood glucose2010

    • Author(s)
      R. Kato, M. Munkhjapgal, D. Takahashi, T. Arakawa, H. Kudo, K. Mitsubayashi
    • Journal Title

      Biosensors and Bioelectronics

      Volume: 26 Pages: 1455-1459

  • [Journal Article] Soft-MEMS glucose sensor with functional polymers2010

    • Author(s)
      S. Iguchi, M. K. Chu, D. Takahashi, T. Arakawa, H. Kudo, K. Mitsubayashi
    • Journal Title

      Journal of Photopolymer Science and Technology

      Volume: 23 Pages: 167-170

  • [Journal Article] Tonometric biosensor with a differential pressure sensor for chemo-mechanical measurement of glucose2009

    • Author(s)
      K. Mitsubayashi, T. Ohgoshi, T. Okamoto, Y. Wakabayashi, M. Kozuka, K. Miyajima, H. Saito, H. Kudo
    • Journal Title

      Biosens Bioelectron

      Volume: 24 Pages: 1518-1521

  • [Journal Article] A soft and flexible biosensor using a phospholipid polymer for continuous glucose monitoring2009

    • Author(s)
      M. X. Chu, H. Kudo, T. Shirai, K. Miyajima, H. Ssaito, N. Morimoto, K. Yano, Y. Iwasaki, K. Akiyoshi, K. Mitsubayashi
    • Journal Title

      Biomed Microdevices

      Volume: 11 Pages: 837-842

  • [Presentation] Bio-inspired self-regulation system of glucose level with chemo-mechanical energy conversion bio-membrane2011

    • Author(s)
      Munkhjargal M, Kato R, Miyajima K, Arakawa T, Kudo H, Mitsubayashi K.
    • Organizer
      International Bionic Engineering Conference2011
    • Place of Presentation
      Boston, USA
    • Year and Date
      2011-09-18
  • [Presentation] An autonomous drug-release system based on chemo-mechanical energy conversion for blood sugar control2010

    • Author(s)
      M. Munkhjargal, R. Kato, D. Takahashi, T. Arakawa, H. Kudo, K. Mitsubayashia
    • Organizer
      Pacifichem 2010
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2010-12-15
  • [Presentation] Bio-energetic self-regulation system of glucose level with chemo-mechanical drug release function2010

    • Author(s)
      R. Kato, D. Takahashi, T. Arakawa, H. Kudo, K. Mitsubayashi
    • Organizer
      20th Anniv. meeting of World Congress on Biosensors
    • Place of Presentation
      Glasgow, UK
    • Year and Date
      2010-05-26
  • [Presentation] Autonomous Biosensors & BioSystem with Organic Engine(Bio-energetic intelligent function using artificial active transportation)2010

    • Author(s)
      K. Mitsubayashi
    • Organizer
      6th Sweden-Japan Workshop on BioNano Technology
    • Place of Presentation
      Mishima, Japan
    • Year and Date
      2010-05-12
  • [Presentation] Intelligent kinetic biosensors with visible motions to target analyte2009

    • Author(s)
      T. Okamoto, D. Takahashi, T. Arakawa, H. Kudo, K. Mitsubayashi
    • Organizer
      First Bio-Sensing Technology Conference
    • Place of Presentation
      Bristol, UK
    • Year and Date
      2009-11-12
  • [Presentation] Bio-transducers for biomedical applications2009

    • Author(s)
      K. Mitsubayashi
    • Organizer
      2009International Conference on Solid State Devices and Materials(SSDM2009)
    • Place of Presentation
      Sendai, Japan
    • Year and Date
      2009-10-07
  • [Presentation] Kinetic Biosensors with Intelligent Visible Motions for Chemical Analytes2009

    • Author(s)
      Y. Wakabayashi, T. Okamoto, K. Miyajima, D. Takahashi, T. Arakawa, H. Kudo, K. Mitsubayashi
    • Organizer
      Euroanalysis2009
    • Place of Presentation
      Innsbruck, Austria
    • Year and Date
      2009-09-06
  • [Book] 第17章次世代医療・ヘルスケアのためのウエアラブルセンサ,ヘルスケアとバイオ医療のための先端デバイス機器2009

    • Author(s)
      工藤寛之、三林浩二
    • Publisher
      CMC出版

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Published: 2013-07-31   Modified: 2017-10-16  

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