2011 Fiscal Year Final Research Report
Molecular genetic analysis of hybrid vigor and inbreeding depression utilizing recombinant inbred mouse strains
Project/Area Number |
21650097
|
Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
Allocation Type | Single-year Grants |
Research Field |
Laboratory animal science
|
Research Institution | Shinshu University |
Principal Investigator |
MORI Masayuki 信州大学, 医学系研究科, 准教授 (60273190)
|
Project Period (FY) |
2009 – 2011
|
Keywords | リコンビナント近交系 / 雑種強勢 / 近交退化 / マウス |
Research Abstract |
It was revealed that the hybrid mice from genetically distant SM/J and A/J mouse strains showed superiority to the parental strains in growth and breeding performances. It was suggested that the recombinant inbred mouse strains derived from SM/J and A/J would be a valuable tool for elucidation of the mechanisms of hybrid vigor and inbreeding depression.
|
Research Products
(12 results)