2011 Fiscal Year Final Research Report
Reconstruction of liver on avian chorioallantoic membrane for the hepatic transplantation.
| Project/Area Number |
21659317
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Digestive surgery
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| Research Institution | Niigata University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
|
| Keywords | 肝臓外科学 / 心・肝混合細胞 / 共培養 / 鳥類漿尿膜 / 肝臓再生 / 類洞形成 / 内皮細胞 / 造血 |
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| Research Abstract |
In order to reconstruct the liver which has an suitable size for the transplant, the developing chick liver cells cultured on the avian chorioallantoic membrane. Whenliver cells cultured with cardiac cells, large sized reconstructed liver was obtainedreadily. In this liver, it was indicated that hepatocytes changed their embryonic character to that of adult type. This phenomenon may be advantageous for the transplantation.
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