2011 Fiscal Year Final Research Report
Technical development of magnetic hyperthermia toward precise temperature control
| Project/Area Number |
21680038
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | National Institute of Advanced Industrial Science and Technology (2010-2011)
Tohoku University (2009) |
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Principal Investigator |
KASUYA Ryo 独立行政法人産業技術総合研究所, サステナブルマテリアル研究部門, 研究員 (50509734)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 構造・機能材料 / ナノ材料 / 磁性 / 細胞・組織 / ナノバイオ |
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| Research Abstract |
For the application of magnetic hyperthermia, the heat source of magnetite nanoparticles (MNPs) were synthesized by a thermal decomposition method. The average diameter (D_<av>) of MNPs increased from 6.6 to 12.5 nm with increasing reaction temperature from 200 to 250.C. The heat dissipation efficiency was 22.5 W/g for the MNPs with D_<av> of 12.5 nm, while those with D_<av> of 6.6 nm did not generate any significant heat. The surface modification of amphiphilic co-polymer was applied to disperse MNPs in water and buffer solution.
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