2011 Fiscal Year Final Research Report
Development of fusion molecular imaging technique based on functional molecular design
| Project/Area Number |
21685019
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemistry related to living body
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| Research Institution | Osaka University |
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Principal Investigator |
MIZUKAMI Shin 大阪大学, 大学院・工学研究科, 准教授 (30420433)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 蛍光プローブ / MRI / ラベル化 / イメージング / β-ラクタマーゼ |
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| Research Abstract |
Several elemental technologies for next-generation molecular imaging methods were developed by integrating chemical principle-based functional probe design, protein engineering, and latest instrumental analyses. Specifically, three technologies, which are^19F MRI detection system to visualize living cellular gene expression, novel protein labeling technology, and time-resolved photoluminescence imaging technology for proteins, were developed.
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