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2010 Fiscal Year Final Research Report

Development of bio-actuator constructed by magnetic force-based tissue engineering

Research Project

  • PDF
Project/Area Number 21686079
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Biofunction/Bioprocess
Research InstitutionKyushu University

Principal Investigator

ITO Akira  Kyushu University, 大学院・工学研究院, 准教授 (60345915)

Project Period (FY) 2009 – 2010
Keywordsティッシュエンジニアリング / 磁性ナノ粒子 / バイオアクチュエータ / 骨格筋
Research Abstract

If an artificial skeletal muscle can be applied as an actuator, it may exhibit high energy conversion efficiency. In this study, we successfully constructed three-dimensional tissue-like structures composed of myoblast cells by using a magnetic force-based tissue engineering technique. The tissue contracted rhythmically in response to electrical pulses. Moreover, we constructed genetically engineered myoblast cells to promote their performance as bio-actuator.

  • Research Products

    (19 results)

All 2011 2010 2009 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (13 results) Remarks (3 results)

  • [Journal Article] Functional Evaluation of Artificial Skeletal Muscle Tissue Constructs Fabricated by a Magnetic Force-Based Tissue Engineering Technique.2011

    • Author(s)
      Yasunori Yamamoto, Akira Ito, Hideaki Fujita, Eiji Nagamori, Yoshinori Kawabe, Masamichi Kamihira
    • Journal Title

      Tissue Engineering Part A 17(1-2)

      Pages: 107-114

    • Peer Reviewed
  • [Journal Article] Construction of Cardiac Tissue Rings Using a Magnetic Tissue Fabrication Technique.2010

    • Author(s)
      Hirokazu Akiyama, Akira Ito, Masanori Sato, Yoshinori Kawabe, Masamichi Kamihira
    • Journal Title

      International Journal of Molecular Sciences 11(8)

      Pages: 2910-2920

    • Peer Reviewed
  • [Journal Article] Genetically Engineered Angiogenic Cell Sheets Using Magnetic Force-Based Gene Delivery and Tissue Fabrication Techniques.2010

    • Author(s)
      Hirokazu Akiyama, Akira Ito, Yoshinori Kawabe, Masamichi Kamihira
    • Journal Title

      Biomaterials 31(6)

      Pages: 1251-1259

    • Peer Reviewed
  • [Presentation] Fabrication of Artificial Skeletal Muscle Tissues by a Magnetic Force-Based Tissue Engineering Technique.2010

    • Author(s)
      Yasunori Yamamoto, Akira Ito, Yoshinori Kawabe, Masamichi Kamihira
    • Organizer
      The 16th Symposium of Young Asian Biochemical Engineers' Community (YABEC 2010)
    • Place of Presentation
      元智大学(台湾)
    • Year and Date
      2010-11-10
  • [Presentation] Fabrication of Angiogenic Gene-Modified Myoblast Cell Sheets Using Magnetic Tissue Engineering Techniques.2010

    • Author(s)
      Hirokazu Akiyama Akira Ito, Yoshinori Kawabe, Masamichi Kamihira
    • Organizer
      International Conference on Chemical Engineering 2010
    • Place of Presentation
      サンフランシスコ(アメリカ)
    • Year and Date
      2010-10-21
  • [Presentation] Magnetic Force-Based Tissue Engineering of Skeletal Muscle.2010

    • Author(s)
      Yasunori Yamamoto, Akira Ito, Hideaki Fujita, Eiji Nagamori, Yoshinori Kawabe, Masamichi Kamihira
    • Organizer
      14th International Biotechnology Symposium and Exhibition
    • Place of Presentation
      リミニ(イタリア)
    • Year and Date
      2010-09-14
  • [Presentation] IGF-I遺伝子導入による高機能筋芽細胞の作製2010

    • Author(s)
      佐藤暢哲, 井藤彰, 河邉佳典, 長森英二, 上平正道
    • Organizer
      化学工学会第42回秋季大会
    • Place of Presentation
      同志社大学(京都市)
    • Year and Date
      2010-09-06
  • [Presentation] ティッシュエンジニアリングによる筋組織構築とバイオアクチュエータへの応用2010

    • Author(s)
      井藤彰, 河邉佳典, 長森英二, 上平正道
    • Organizer
      化学工学会第42回秋季大会
    • Place of Presentation
      同志社大学(京都市)
    • Year and Date
      2010-09-06
  • [Presentation] バイオアクチュエータのためのIGF-I遺伝子導入筋芽細胞の作製2010

    • Author(s)
      佐藤暢哲, 井藤彰, 河邉佳典, 藤田英明, 長森英二, 上平正道
    • Organizer
      第47回化学関連支部合同九州大会
    • Place of Presentation
      北九州国際会議所(北九州市)
    • Year and Date
      2010-07-10
  • [Presentation] 機能性磁性ナノ粒子を用いて作製した人工筋組織の機能評価2010

    • Author(s)
      山本泰徳, 井藤彰, 河邉佳典, 藤田英明, 長森英二, 上平正道
    • Organizer
      化学工学会第75年会
    • Place of Presentation
      鹿児島大学(鹿児島市)
    • Year and Date
      2010-03-20
  • [Presentation] Construction of Skeletal Muscular Tissue-Like Structures by a Magnetic Force-Based Tissue Engineering Technique.2009

    • Author(s)
      Yasunori Yamamoto, Akira Ito, Hideaki Fujita, Eiji Nagamori, Yoshinori Kawabe, Masamichi Kamihira
    • Organizer
      APBioChEC2009
    • Place of Presentation
      神戸市
    • Year and Date
      2009-11-23
  • [Presentation] Skeletal Muscle Tissue Engineering Using Functional Magnetite Nanoparticles.2009

    • Author(s)
      Akira Ito, Hirokazu Akiyama, Yasunori Yamamoto, Yoshinori Kawabe, Masamichi Kamihira
    • Organizer
      MHS2009
    • Place of Presentation
      名古屋市
    • Year and Date
      2009-11-10
  • [Presentation] 機能性磁性ナノ粒子を用いた筋組織再生技術によるバイオアクチュエータの開発2009

    • Author(s)
      井藤彰, 山本泰徳, 河邉佳典, 藤田英明, 清水一憲, 長森英二, 上平正道
    • Organizer
      第2回化学工学3支部合同北九州大会
    • Place of Presentation
      北九州市
    • Year and Date
      2009-10-31
  • [Presentation] 磁力を用いたティッシュエンジニアリング技術による筋組織の構築2009

    • Author(s)
      井藤彰
    • Organizer
      第61回日本生物工学会大会
    • Place of Presentation
      名古屋市
    • Year and Date
      2009-09-25
  • [Presentation] 血管新生因子を遺伝子導入した細胞シートの作製と評価2009

    • Author(s)
      秋山弘和, 井藤彰, 河邉佳典, 上平正道
    • Organizer
      第61回日本生物工学会大会
    • Place of Presentation
      名古屋市
    • Year and Date
      2009-09-23
  • [Presentation] 磁力を用いた筋組織構築法の開発2009

    • Author(s)
      山本泰徳, 井藤彰, 河邉佳典, 藤田英明, 長森英二, 上平正道
    • Organizer
      第46回化学関連支部合同九州大会
    • Place of Presentation
      北九州市
    • Year and Date
      2009-07-11
  • [Remarks] ホームページ等

  • [Remarks]

    • URL

      http://hyoka.ofc.kyushu-u.ac.jp/search/details/K002906/index.html

  • [Remarks]

    • URL

      http://www.chem-eng.kyushu-u.ac.jp/lab3/index.html

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Published: 2012-02-13   Modified: 2016-04-21  

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