2011 Fiscal Year Final Research Report
Identificationand the analysis of the genes involvedin photoreceptor morphogenesis and maintenance in Drosophila
| Project/Area Number |
21687005
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Animal physiology/Animal behavior
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| Research Institution | Hiroshima University (2011)
Nagoya University (2009-2010) |
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Principal Investigator |
SATOH Akiko 広島大学, 大学院・総合科学研究科, 准教授 (30529037)
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| Project Period (FY) |
2009 – 2011
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| Keywords | ショウジョウバエ / 視細胞 / ロドプシン・アレスチン / GPI結合タンパク質 / トランスゴルジネットワーク |
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| Research Abstract |
We screened to identify new genes involved in Rhodopsin transport andfound two that the deficiency of glycosylphosphatidylinositol (GPI) synthesis/attachment processes causes the loss of the apical transport of Rhodopsinfrom the TGN (Development, 2013). In the process of studying Arrstin mediated signaling, we found that Arr2 translocation in Drosophilaphotoreceptors is driven by diffusion, but profoundly accelerated by phototransduction and Ca2+influx (Neuron 2010, J. Neursci. 2012)
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