2011 Fiscal Year Final Research Report
Regulation of cells function by light technology
| Project/Area Number |
21687011
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biophysics
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| Research Institution | Osaka University |
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Principal Investigator |
KUSHIBIKI Toshihiro 大阪大学, 臨床医工学融合研究教育センター, 招へい准教授 (30403158)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 光 / レーザー / 細胞 / 機能制御 / 光線力学療法 |
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| Research Abstract |
The regulations of cells function by using noninvasive methods are the effective tools not only for treatment and prevent diseases but also basic biomedical researches. The objective of this research is the application of laser and light technology for the regulation of cells function. In the results, I found that intracellular reactive oxygen species were increased after laser(wavelength : 405 nm) irradiation, following NF-κB and MAPK phosphorylation. These results suggest that the laser light is one of the effective tools for the regulation of cells function.
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