2010 Fiscal Year Final Research Report
Visualization analysis of network physiology and anatomy of the amygdala-focusing on olfaction-
| Project/Area Number |
21700389
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | National Institute of Advanced Industrial Science and Technology |
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Principal Investigator |
KAJIWARA Riichi National Institute of Advanced Industrial Science and Technology, バイオメディカル研究部門, 主任研究員 (60356772)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 神経回路網 / 神経活動イメージング / 扁桃体 / 嗅内皮質 / 梨状皮質 / 嗅覚 |
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| Research Abstract |
In order to reveal the functional organization of the amygdaloid network, we developed the optical recording system using a guinea pig isolated whole brain. By using this experimental setup, we analyzed the dependency of stimulus intensity and frequency on the spatiotemporal patterns of the neural activity evoked by the electrical shock to olfactory nerve. In addition to the imaging study, laminar profiles of evoked field potentials were recorded in the amygdala using a multichannel silicon probe. Current source density analysis performed on the field responses revealed the propagation pattern of the neural activity in the deep structure of the amygdaloid cortex.
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