2010 Fiscal Year Final Research Report
Chromatin Dynamics during Neuronal Differentiation
| Project/Area Number |
21700404
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurochemistry/Neuropharmacology
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| Research Institution | Osaka University |
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Principal Investigator |
SUGO Noriyuki Osaka University, 大学院・生命機能研究科, 助教 (20372625)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 発生・分化・老化 / 遺伝子発現調節 / クロマチン / DNA修復 |
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| Research Abstract |
Molecular mechanism of neuronal differentiation including transcription and chromatin regulation has remained unclear. In this study, we revealed that that histone deacetylase (HDAC) and DNA repair protein play a critical role in cortical differentiation.
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