2010 Fiscal Year Final Research Report
Analysis of activity-dependent myelination in optic nerve.
| Project/Area Number |
21700418
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurochemistry/Neuropharmacology
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| Research Institution | National Institute for Physiological Sciences |
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Principal Investigator |
INAMURA Naoko National Institute for Physiological Sciences, 分子生理研究系, 特別協力研究員 (20397623)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 神経科学 / 神経化学 / 神経発生学 / ミエリン / グリア |
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| Research Abstract |
Myelination is important for rapid electric signal transduction in neural circuit formation. To analyze the mechanism of activity-dependent myelination we examined using optic nerve. Effective sparse labeling of oligodendrocyte was observed. Additionally a mouse line enable to manipulate gene expression in mature oligodendrocyte was generated.
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