2010 Fiscal Year Final Research Report
Connection Specificity in Cortical Circuits
| Project/Area Number |
21700438
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | National Institute for Physiological Sciences |
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Principal Investigator |
OTSUKA Takeshi National Institute for Physiological Sciences, 大脳皮質機能研究系, 助教 (10390692)
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| Project Period (FY) |
2009 – 2010
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| Keywords | 大脳皮質 / 錐体細胞 / 介在細胞 / FS細胞 / マルティノッティ細胞 |
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| Research Abstract |
I investigated how inhibitory interneurons are incorporated into excitatory subnetworks in cortical circuits to understand information processing of the cortex. Whole-cell recordings were obtained from layer 5 (L5) pyramidal cells and inhibitory interneruons in rat frontal cortical slices. I examined connection specificity between pyramidal cells and inhibitory interneurons. My results suggest that L5 interneurons form distinct intralaminar and interlaminar subnetworks with pyramidal cells, depending on inhibitory cell types.
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