Development of hydrodynamic levitated centrifugal blood pump for long-term circulatory assist

2011 Fiscal Year Final Research Report

• Project/Area Number: 21700479
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Biomedical engineering/Biological material science
• Research Institution: National Institute of Advanced Industrial Science and Technology
• Principal Investigator: KOSAKA Ryou 独立行政法人産業技術総合研究所, ヒューマンライフテクノロジー研究部門, 研究員 (10415680)
• Project Period (FY): 2009 – 2011
• Keywords: 人工臓器工学 / 再生医工学

Research Abstract

The purpose of this study is to investigate the bearing-gap control for the hydrodynamic-bearing pump to prevent hemolysis. As a result, we confirmed that the hemolysis of was improved by balancing the resultant force acting on the impeller.

Research Products

• [Journal Article] Improvement of hemocompatibility for hydrodynamic levitation centrifugal pump by optimizing step bearings (2011)
  • Author(s): Kosaka R, Yada T, Nishida M, Maruyama O, Yamane T
  • Journal Title: Proc. of the IEEE EMBS Pages: 1331-1334
  • DOI: DOI:10.1109/IEMBS.2011.6090313
  • Peer Reviewed
• [Journal Article] Improvement of Hemocompatibility in a Centrifugal Blood Pump with Hydrodynamic Bearings and a Semi-Open Impeller (2009)
  • Author(s): Kosaka R, Maruyama O, Nishida M, Saito S, Hirai S, Yamane T
  • Journal Title: Artif Organs Volume: 33 Pages: 798-804
  • DOI: DOI:10.1111/j.1525-1594.2009.00817.x
  • Peer Reviewed
• [Journal Article] 補助循環用動圧浮上式遠心血液ポンプの動圧軸受隙間評価 (2009)
  • Author(s): 吉田文彦、小阪亮、西田正浩、丸山修、矢田亨、川口靖夫、山根隆志
  • Journal Title: 生体医工学シンポジウム Pages: 190-197
  • Peer Reviewed
• [Presentation] 動圧軸受式遠心血液ポンプのインペララジアル安定性と溶血特性 (2012)
  • Author(s): 安井和哉、小阪亮, 他
  • Organizer: 平成23年度第11回産総研・産技連LS-BT合同研究発表会
  • Place of Presentation: つくば
  • Year and Date: 2012-01-31
• [Presentation] 動圧軸受式遠心ポンプのラジアル運動安定性と溶血特性 (2011)
  • Author(s): 安井和哉、小阪亮, 他
  • Organizer: 第49回日本人工臓器学会大会
  • Place of Presentation: 東京
  • Year and Date: 2011-11-26
• [Presentation] Effect of the Groove on Hydrodynamic Journal Bearing to Impeller Radial Stability and Hemolytic Property of a Centrifugal Blood Pump (2011)
  • Author(s): Yasui K, Kosaka R, et. al
  • Organizer: 19th Congress of the ISRBP
  • Place of Presentation: Louisville, USA
  • Year and Date: 2011-09-09
• [Presentation] Improvement of hemocompatibility for hydrodynamic levitation centrifugal pump by optimizing step bearings (2011)
  • Author(s): Kosaka R, et. al
  • Organizer: IEEE EMBS 2011
  • Place of Presentation: Boston, USA
  • Year and Date: 2011-08-31
• [Presentation] 遠心血液ポンプの動圧軸受形状がインペララジアル安定性と溶血に及ぼす影響 (2011)
  • Author(s): 安井和哉、小阪亮, 他
  • Organizer: 2011年茨城講演会
  • Place of Presentation: 茨城大
  • Year and Date: 2011-08-26
• [Presentation] 流体力を利用した動圧浮上遠心血液ポンプの軸受隙間の至適化 (2010)
  • Author(s): 小阪亮, 他
  • Organizer: 第48回日本人工臓器学会大会
  • Place of Presentation: 仙台
  • Year and Date: 2010-11-18
• [Presentation] Development of hydrodynamic levitation centrifugal blood pump and mass-flow meter (2010)
  • Author(s): 小阪亮
  • Organizer: Scientific meeting in Aston University
  • Place of Presentation: Aston University(England)
  • Year and Date: 2010-10-18
• [Presentation] Bearing gap control for a hydrodynamic-bearing centrifugal pump from the viewpoint of hemolysis improvement (2010)
  • Author(s): Kosaka R, et. al
  • Organizer: 18th Congress of the ISRBP
  • Place of Presentation: Berlin
  • Year and Date: 2010-10-15
• [Presentation] 神への挑戦:人工心臓 (2010)
  • Author(s): 小阪亮
  • Organizer: 富山大学夢大学in工学部2010
  • Place of Presentation: 富山
  • Year and Date: 2010-10-02
• [Presentation] 長期耐久性と信頼性を目指した動圧浮上遠心血液ポンプの開発 (2010)
  • Author(s): 小阪亮, 他
  • Organizer: 第22回「電磁力関連のダイナミクス」シンポジウム
  • Place of Presentation: 門司
  • Year and Date: 2010-05-21
• [Presentation] Development of hydrodynamic levitation centrifugal blood pump and mass-flow meter (2009)
  • Author(s): 小阪亮
  • Organizer: Scientific meeting in Chulalongkorn University
  • Place of Presentation: Chulalongkorn University(Thailand)
  • Year and Date: 2009-10-05
• [Presentation] Development of hydrodynamic levitation centrifugal blood pump for high durability LVAS (2009)
  • Author(s): Kosaka R, et. al
  • Organizer: 17th Congress of the ISRBP
  • Place of Presentation: Singapore
  • Year and Date: 2009-10-02
• [Presentation] 補助循環用動圧浮上式遠心血液ポンプの動圧軸受隙間評価 (2009)
  • Author(s): 吉田文彦、小阪亮, 他
  • Organizer: 生体医工学シンポジウム2009
  • Place of Presentation: 千葉県千葉市
  • Year and Date: 2009-09-25
• [Presentation] 補助循環用動圧浮上式遠心血液ポンプの動圧軸受の隙間評価 (2009)
  • Author(s): 吉田文彦、小阪亮, 他
  • Organizer: 日本機械学会茨城講演会2009
  • Place of Presentation: つくば
  • Year and Date: 2009-08-25
• [Remarks] 「大人の社会科見学:人工心臓の開発について」、美的生活Blife 8月号、pp. 26、株式会社ワイズガイ、2009/07/06
• [Patent(Industrial Property Rights)] 遠心血液ポンプ (2012)
  • Inventor(s): 小阪亮、山根隆志、安井和哉
  • Industrial Property Rights Holder: 小阪亮、山根隆志、安井和哉
  • Industrial Property Number: 特許、特願2012-083186
  • Filing Date: 2012-03-30
• [Patent(Industrial Property Rights)] 遠心血液ポンプ (2012)
  • Inventor(s): 小阪亮
  • Industrial Property Rights Holder: 小阪亮
  • Industrial Property Number: 特許、特願2012-083211
  • Filing Date: 2012-03-30
• [Patent(Industrial Property Rights)] 動圧軸受を備えた人工心臓ポンプ (2011)
  • Inventor(s): 山根隆志、小阪亮、齊藤栄、平井収作
  • Industrial Property Rights Holder: 山根隆志、小阪亮、齊藤栄、平井収作
  • Industrial Property Number: 特許、特4866704
  • Acquisition Date: 2011-11-18