2011 Fiscal Year Final Research Report
Elucidation of the mechanism ameliorating contractile ability of atrophied skeletal muscle
| Project/Area Number |
21700558
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Suzuka University of Medical Science (2010-2011)
Himeji Dokkyo University (2009) |
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Principal Investigator |
SASAI Nobuaki 鈴鹿医療科学大学, 保健衛生学部, 准教授 (20454762)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 理学療法学 / 筋収縮力の回復 |
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| Research Abstract |
Skeletal muscle atrophy and hypertrophy involve the regulation of protein synthesis which is caused by alterations in mechanical stress against the muscle, which is indicated from data of denervation atrophy in rat and stretch-induced hypertrophy of cultured cell in this project. Furthermore, the disused-atrophy model of mouse tail-suspension has been established in our laboratory. This model will allow for more detail analyses on the relation between cell signaling and the recovery of muscle force generating capacity.
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