2010 Fiscal Year Final Research Report
Analysis of the molecular mechanisms of acquired radioresistance induced by fractionated radiation
Project/Area Number |
21710054
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Risk sciences of radiation/Chemicals
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Research Institution | Tohoku University |
Principal Investigator |
SHIMURA Tsutomu Tohoku University, 加齢医学研究所, 助教 (40463799)
|
Project Period (FY) |
2009 – 2010
|
Keywords | 放射線 / がん |
Research Abstract |
We have demonstrated that tumor radioresistance can be suppressed by down-regulation of AKT/GSK3beta/cyclin D1 pathway. Manipulation of cyclin D1 is useful to enhance the efficacy of radiotherapy.
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