2011 Fiscal Year Final Research Report
Developing a novel bioassay method using surface-enhanced laser desorption/ionization mass spectrometry for detecting toxic materials.
| Project/Area Number |
21710070
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Risk sciences of radiation/Chemicals
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| Research Institution | Tokyo University of Pharmacy and Life Science |
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Principal Investigator |
AOKI Motohide 東京薬科大学, 生命科学部, 助教 (30418917)
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| Project Period (FY) |
2009 – 2011
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| Keywords | 環境分析 / 質量分析法 / 環境評価 / バイオマーカー |
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| Research Abstract |
For more effective and efficient chemical risk management, a novel bioassay method for detecting toxic materials in the environment using surface-enhanced laser desorption/ionization mass spectrometry(SELDI-MS) was developed. The established SELDI-MS protocol for collecting the response patterns to toxic materials in the protein profile of microalgae as a biological indicator of environment allows to efficiently searching for biomarkers responding to toxic materials and to detecting the hazardous substances.
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