2010 Fiscal Year Final Research Report
Study on Dynamic Behavior of Water-Soluble Fullerene Nanoparticle having a Fluorescent Tag for Bioimaging
| Project/Area Number |
21710109
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Osaka University |
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Principal Investigator |
KOKUBO Ken Osaka University, 工学研究科, 講師 (20304008)
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| Project Period (FY) |
2009 – 2010
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| Keywords | ナノ粒子 / ナノチューブ |
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| Research Abstract |
We succeeded in synthesizing fullerenols having pyrene moieties as a fluorescent tag and found that the excimer emission and the fluorescent lifetime were varied by changing the linker length. We also synthesized a fullerenol having a fluorescein moiety which shows much stronger fluorescence in visible region. The fluorescent quenching experiments revealed that the fluorescent quenching by energy transfer from fluorophore to fullerene nucleus was retarded by 2.5 times for fluorescein as compared with that for pyrene fluorophore. The fluorescent quantum yield of fluorescein tagged fullerenol was thus improved ca. 2 times higher than that of pyrene tagged fullerenol.
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