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2010 Fiscal Year Final Research Report

Construction of Separation Systems for Biomacromolecules by Using Self-Organized Nanotube Hydrogels

Research Project

  • PDF
Project/Area Number 21710117
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Nanomaterials/Nanobioscience
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

KAMETA Naohiro  National Institute of Advanced Industrial Science and Technology, ナノチューブ応用研究センター研, 研究員 (20517297)

Project Period (FY) 2009 – 2010
Keywordsナノ材料 / 自己組織化 / ナノチューブ / ハイドロゲル / DNA / 分離
Research Abstract

Novel wedge-shaped amphiphiles self-organized in water to from nanotube hydrogels responding on pH stimulus. The nanotube hydrogel possessed two independent spaces consisting of three-dimensional meshworks formed between nanotubes and one-dimensional hollow cylinder of the nanotube itself. Introduction of the nanotube hydrogel as sieves into the capillary electrophoresis allowed to construct a separation system for biomacromolecules. Imaging technique showed that the one-dimensional hollow cylinder of the nanotube with 8 nm inner diameter acts as a functional space for the DNA separation.

  • Research Products

    (14 results)

All 2011 2010 2009 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (8 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Liquid-Phase Nanospace Chemistry of Self-Organized Nanotube Channels2011

    • Author(s)
      Naohiro Kameta
    • Journal Title

      Bunseki Kagaku

    • Peer Reviewed
  • [Journal Article] Photo-Responsive Soft Nanotubes for Controlled Guest Release2011

    • Author(s)
      Naohiro Kameta, Asuka Tanaka, Haruhisa Akiyama, Hiroyuki Minamikawa, Mitsutoshi Masuda, Toshimi Shimizu
    • Journal Title

      Chemistry-A European Journal vol.17

      Pages: 5251-5255

    • Peer Reviewed
  • [Journal Article] Confinement Effect of Organic Nanotubes Toward Green Fluorescent Proteins (GFP) Depending on the Inner Diameter Size2010

    • Author(s)
      Naohiro Kameta, Hiroyuki Minamikawa, Yuu Someya, Hiroharu Yui, Mitsutoshi Masuda, Toshimi Shimizu
    • Journal Title

      Chemistry-A European Journal,インサイドカバー, Very Important Paper vol.16

      Pages: 4217-4223

    • Peer Reviewed
  • [Journal Article] Supramolecular Nanotube Hydrogels : Remarkable Resistance Effect of Confined Proteins to Denaturants2009

    • Author(s)
      Naohiro Kameta, Kaname Yoshida, Mitsutoshi Masuda, Toshimi Shimizu
    • Journal Title

      Chemistry of Materials vol.21

      Pages: 5892-5898

    • Peer Reviewed
  • [Presentation] Organic Nanotubes with a Confinement Nanospace for Biomacromolecules2011

    • Author(s)
      Naohiro Kameta, Mitsutoshi Masuda, Toshimi Shimizu
    • Organizer
      International Conference on Biomaterials Science 2011
    • Place of Presentation
      つくば
    • Year and Date
      2011-03-16
  • [Presentation] Supramolecular Nanotube Hydrogels Having a One-Dimensional Confined Nanospace and Three-Dimensional Meshworks for Proteins2010

    • Author(s)
      Naohiro Kameta, Mitsutoshi Masuda, Toshimi Shimizu
    • Organizer
      Pacifichem2010
    • Place of Presentation
      ハワイ
    • Year and Date
      2010-12-17
  • [Presentation] 有機ナノチューブのナノ空間化学(5):ゲスト放出制御のための光刺激応答性ナノチューブの構築2010

    • Author(s)
      亀田直弘, 田中明日香, 秋山陽久, 南川博之, 増田光俊, 清水敏美
    • Organizer
      第59回高分子学会年次大会
    • Place of Presentation
      横浜
    • Year and Date
      2010-05-28
  • [Presentation] 有機ナノチューブのナノ空間化学(8):ゲストタンパク質の輸送拡散,放出速度,安定性に及ぼすナノチャネルの内径効果2010

    • Author(s)
      亀田直弘, 南川博之, 増田光俊, 清水敏美
    • Organizer
      第71回分析化学討論会
    • Place of Presentation
      島根
    • Year and Date
      2010-05-16
  • [Presentation] 有機ナノチューブのナノ空間化学(1):光刺激応答性ナノチューブの創製とゲスト放出制御2010

    • Author(s)
      亀田直弘, 田中明日香, 秋山陽久, 南川博之, 増田光俊, 清水敏美
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-29
  • [Presentation] 有機ナノチューブ空間のバイオ応用(1):ナノチャネルに包接された生体高分子の動的挙動と安定性2010

    • Author(s)
      亀田直弘, 南川博之, 増田光俊, 清水敏美
    • Organizer
      SORSTシンポジウム(4)ナノ空間材料その特性と魅力
    • Place of Presentation
      東京
    • Year and Date
      2010-01-29
  • [Presentation] Supramolecular Nanotube Hydrogel2009

    • Author(s)
      Naohiro Kameta, Kaname Yoshida, Mitsutoshi Masuda, Toshimi Shimizu
    • Organizer
      GelSympo2009
    • Place of Presentation
      大阪
    • Year and Date
      2009-12-03
  • [Presentation] 超分子ナノチューブハイドロゲルの構築とタンパク質固定化特性2009

    • Author(s)
      亀田直弘, 吉田要, 増田光俊, 清水敏美
    • Organizer
      第58回高分子討論会
    • Place of Presentation
      熊本
    • Year and Date
      2009-09-16
  • [Remarks] ホームページ等

    • URL

      http://unit.aist.go.jp/ntrc/ci/index.html

  • [Patent(Industrial Property Rights)] 光異性化基を有するアミド化合物及び該化合物が自己集合してなる有機ナノチューブ並びにその製造方法2010

    • Inventor(s)
      亀田直弘, 増田光俊, 南川博之, 小木曽真樹, 秋山陽久, 清水敏美
    • Industrial Property Rights Holder
      独立行政法人産業技術総合研究所
    • Industrial Property Number
      特許,特願2009-198319
    • Filing Date
      2010-08-28

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Published: 2012-02-13   Modified: 2016-04-21  

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