2010 Fiscal Year Final Research Report
Construction of Separation Systems for Biomacromolecules by Using Self-Organized Nanotube Hydrogels
Project/Area Number |
21710117
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Nanomaterials/Nanobioscience
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Research Institution | National Institute of Advanced Industrial Science and Technology |
Principal Investigator |
KAMETA Naohiro National Institute of Advanced Industrial Science and Technology, ナノチューブ応用研究センター研, 研究員 (20517297)
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Project Period (FY) |
2009 – 2010
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Keywords | ナノ材料 / 自己組織化 / ナノチューブ / ハイドロゲル / DNA / 分離 |
Research Abstract |
Novel wedge-shaped amphiphiles self-organized in water to from nanotube hydrogels responding on pH stimulus. The nanotube hydrogel possessed two independent spaces consisting of three-dimensional meshworks formed between nanotubes and one-dimensional hollow cylinder of the nanotube itself. Introduction of the nanotube hydrogel as sieves into the capillary electrophoresis allowed to construct a separation system for biomacromolecules. Imaging technique showed that the one-dimensional hollow cylinder of the nanotube with 8 nm inner diameter acts as a functional space for the DNA separation.
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