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2011 Fiscal Year Final Research Report

An autonomous information processing system based on the single-molecular structural transition of genome-size giant DNAs.

Research Project

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Project/Area Number 21710119
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Nanomaterials/Nanobioscience
Research InstitutionTokyo Institute of Technology (2011)
The University of Tokyo (2009-2010)

Principal Investigator

TAKINOUE Masahiro  東京工業大学, 大学院・総合理工学研究科, 講師 (20511249)

Project Period (FY) 2009 – 2011
Keywordsナノバイオ / 非平衡 / 非線形 / DNA / マイクロ流路 / 自律システム
Research Abstract

The construction of micrometer-sized(cell-sized) reaction systems was achieved using microfluidic technologies. The cell-sized reaction system can encapsulate biomolecular systems including DNAs, proteins, etc., and also realizes molecular input/output from/to exterior environments. As a result, the dynamic concentration control of a cell-sized reaction system required for autonomous molecular information processing has been achieved using this device.

  • Research Products

    (21 results)

All 2012 2011 2010 2009 Other

All Journal Article (3 results) (of which Peer Reviewed: 2 results) Presentation (16 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Propelling Microobjects Using AStationary DC Voltage2011

    • Author(s)
      Masahiro Takinoue, Hiroaki Onoe, Daisuke Kiriya, Shoji Takeuchi
    • Journal Title

      Proceedings of The 24th IEEE International Conferenceon Micro Electro Mechanical Systems(MEMS2011)

      Pages: 1173-1176

    • Peer Reviewed
  • [Journal Article] Fusion and fission control of picoliter-sized microdroplets for changing the solution concentration of microreactors2010

    • Author(s)
      Masahiro Takinoue, Hiroaki Onoe, Shoji Takeuchi
    • Volume
      vol.6
    • Peer Reviewed
  • [Journal Article] Solution concentration change of picoliter-sized microdropletreactors2010

    • Author(s)
      Masahiro Takinoue, Hiroaki Onoe, Shoji Takeuchi
    • Journal Title

      Proceedings of The 14thInternational Conference on Miniaturized Systems for Chemistry and Life Sciences(microTAS 2010)

      Pages: 1829-1831

  • [Presentation] 非平衡人工細胞モデルを目指した油中水滴エマルション技術2012

    • Author(s)
      瀧ノ上正浩
    • Organizer
      第4回定量生物学の会,ポスター発表
    • Place of Presentation
      名古屋
    • Year and Date
      2012-07-09
  • [Presentation] Investigation of anonequilibrium artificial cell modelbased on a droplet microfluidics2011

    • Author(s)
      Masahiro Takinoue
    • Organizer
      「細胞を創る」研究会
    • Place of Presentation
      大阪
    • Year and Date
      20111024-28
  • [Presentation] Microfluidic technology toward the construction of nonequilibrium artificial cells2011

    • Author(s)
      瀧ノ上正浩
    • Organizer
      日本生物物理学会第49回年会,口頭発表
    • Place of Presentation
      姫路
    • Year and Date
      20110916-18
  • [Presentation] 非平衡人工細胞モデルのためのW/Omicrodropletの溶液交換2011

    • Author(s)
      瀧ノ上正浩,尾上弘晃,竹内昌治
    • Organizer
      第23回化学とマイクロ・ナノシステム研究会Poster PA19
    • Place of Presentation
      千葉
    • Year and Date
      20110610-11
  • [Presentation] Propelling Microobjects Using A Stationary DC Voltage2011

    • Author(s)
      Masahiro Takinoue, Hiroaki Onoe, Daisuke Kiriya, Shoji Takeuchi
    • Organizer
      The 24thInternational Conference on Micro Electro Mechanical Systems(MEMS2011)
    • Place of Presentation
      Cancun, Mexico
    • Year and Date
      20110123-27
  • [Presentation] 生命の非平衡性・自律性と細胞サイズ反応系2010

    • Author(s)
      瀧ノ上正浩,尾上弘晃,竹内昌治
    • Organizer
      「細胞を創る」研究会3. 0
    • Place of Presentation
      東京
    • Year and Date
      20101212-13
  • [Presentation] Solution Concentration Change Of Picoliter-sized Microdroplet Reactors2010

    • Author(s)
      Masahiro Takinoue, Hiroaki Onoe, Shoji Takeuchi
    • Organizer
      The 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences(microTAS2010)
    • Place of Presentation
      Groningen, The Netherlands
    • Year and Date
      20101003-07
  • [Presentation] 融合分裂を利用したリン脂質ベースの細胞サイズ油中水滴のダイナミック濃度変換2010

    • Author(s)
      Masahiro Takinoue, Hiroaki Onoe, Shoji Takeuchi
    • Organizer
      日本生物物理学会第48回年会
    • Place of Presentation
      仙台
    • Year and Date
      20100920-22
  • [Presentation] ドロップレット溶液交換システム2010

    • Author(s)
      瀧ノ上正浩,尾上弘晃,竹内昌治
    • Organizer
      第21回化学とマイクロ・ナノシステム研究会
    • Place of Presentation
      東京
    • Year and Date
      20100610-11
  • [Presentation] Biophysicalapproach to cell-sized molecularrobots2010

    • Author(s)
      Masahiro Takinoue
    • Organizer
      International Conference on Bioinformatics(InCoB) Tokyo 2010
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2010-09-28
  • [Presentation] 非平衡開放系マイクロチャンバー2010

    • Author(s)
      瀧ノ上正浩,尾上弘晃,竹内昌治
    • Organizer
      第10回東京大学生命科学シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-05-01
  • [Presentation] DNAマイクロカプセルの開発2009

    • Author(s)
      堀内浩太,瀧ノ上正浩,竹内昌治,村田智
    • Organizer
      計測自動制御学会システム・情報部門学術講演会2009(SSI2009)
    • Place of Presentation
      東京
    • Year and Date
      20091224-26
  • [Presentation] Acell-sized semipermeable chamber forbiophysics(生物物理学のための細胞サイズ半透膜チャンバー)2009

    • Author(s)
      Masahiro Takinoue, Shoji Takeuchi
    • Organizer
      日本生物物理学会第47回年会
    • Place of Presentation
      徳島
    • Year and Date
      20091030-1101
  • [Presentation] 細胞サイズの半透膜ケージへの生体高分子のカプセル化.細胞サイズ非平衡開放系.2009

    • Author(s)
      瀧ノ上正浩,竹内昌治
    • Organizer
      「細胞を創る」研究会2. 0
    • Place of Presentation
      東京
    • Year and Date
      20091002-03
  • [Presentation] アルギン酸ゲルビーズを用いたDNAマイクロカプセルの構築2009

    • Author(s)
      堀内浩太,瀧ノ上正浩,竹内昌治,村田智
    • Organizer
      「細胞を創る」研究会2. 0
    • Place of Presentation
      東京
    • Year and Date
      20091002-03
  • [Presentation] Formation of microcompartmentssurrounded by semipermeablemembranes2009

    • Author(s)
      Masahiro Takinoue, Sadao Ota, Satoko Yoshizawa, Aki Adachi, Shoji Takeuchi
    • Organizer
      International Symposium : Innovative Nanoscience ofSupermolecular Motor Proteins(INSMP), Poster Presentation
    • Place of Presentation
      Japan
    • Year and Date
      20090908-10
  • [Book] DNAナノエンジニアリングナチュラルコンピューティング・シリーズ第2巻2011

    • Author(s)
      小宮健,瀧ノ上正浩,田中文昭,浜田省吾,村田智,萩谷昌己,横森貴
    • Total Pages
      202
    • Publisher
      近代科学社
  • [Remarks]

    • URL

      http://www.lifephys.dis.titech.ac.jp/

URL: 

Published: 2013-07-31  

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